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Homeobox genes gain trimethylation of histone H3 lysine 4 in glioblastoma tissue

Glioblastoma multiforme (GBM) exhibits considerable heterogeneity and associates with genome-wide alterations of the repressed chromatin marks DNA methylation and H3 lysine 27 trimethylation (H3K27me3). Tri-methylation on lysine 4 of histone H3 (H3K4me3) is an activating epigenetic mark that is enri...

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Detalles Bibliográficos
Autores principales: Luo, Kun, Luo, Donghui, Wen, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5293576/
https://www.ncbi.nlm.nih.gov/pubmed/27160082
http://dx.doi.org/10.1042/BSR20160028