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A cell-permeable tool for analysing APP intracellular domain function and manipulation of PIKfyve activity
The mechanisms for regulating PIKfyve complex activity are currently emerging. The PIKfyve complex, consisting of the phosphoinositide kinase PIKfyve (also known as FAB1), VAC14 and FIG4, is required for the production of phosphatidylinositol 3,5-bisphosphate [PI(3,5)P(2)]. PIKfyve function is requi...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5293579/ https://www.ncbi.nlm.nih.gov/pubmed/26934981 http://dx.doi.org/10.1042/BSR20160040 |