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A cell-permeable tool for analysing APP intracellular domain function and manipulation of PIKfyve activity

The mechanisms for regulating PIKfyve complex activity are currently emerging. The PIKfyve complex, consisting of the phosphoinositide kinase PIKfyve (also known as FAB1), VAC14 and FIG4, is required for the production of phosphatidylinositol 3,5-bisphosphate [PI(3,5)P(2)]. PIKfyve function is requi...

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Detalles Bibliográficos
Autores principales:	Guscott, Benjamin, Balklava, Zita, Safrany, Stephen T., Wassmer, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2016
Materias:	Original Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5293579/ https://www.ncbi.nlm.nih.gov/pubmed/26934981 http://dx.doi.org/10.1042/BSR20160040

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