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MicroRNA-9 inhibits high glucose-induced proliferation, differentiation and collagen accumulation of cardiac fibroblasts by down-regulation of TGFBR2

To investigate the effects of miR-9 on high glucose (HG)-induced cardiac fibrosis in human cardiac fibroblasts (HCFs), and to establish the mechanism underlying these effects. HCFs were transfected with miR-9 inhibitor or mimic, and then treated with normal or HG. Cell viability and proliferation we...

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Detalles Bibliográficos
Autores principales: Li, Jiaxin, Dai, Yingnan, Su, Zhendong, Wei, Guoqian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5293584/
https://www.ncbi.nlm.nih.gov/pubmed/27756824
http://dx.doi.org/10.1042/BSR20160346