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Forkhead box O (FOXO) 3 modulates hypoxia-induced autophagy through AMPK signalling pathway in cardiomyocytes

Autophagy is promoted as a response to such environmental stress conditions as ATP depletion and excessive accumulation of reactive oxygen species (ROS). Multiple signalling pathways, including AMP-activated protein kinase (AMPK), are indicated to promote autophagy in ischaemic/hypoxic (I/R) heart....

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Detalles Bibliográficos
Autores principales: Chi, Yunpeng, Shi, Conghong, Zhao, Yang, Guo, Chengjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5293586/
https://www.ncbi.nlm.nih.gov/pubmed/27129298
http://dx.doi.org/10.1042/BSR20160091