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Acute alloxan renal toxicity in the rat initially causes degeneration of thick ascending limbs of Henle
Alloxan (AL) is a material well-known to induce diabetes. Prior to inducing a prolonged diabetic state, AL causes acute tubulointerstitial nephritis. However, the precise primary target site and mechanism of its nephrotoxicity remain unclear. The objective of this study was to evaluate the morpholog...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Japanese Society of Toxicologic Pathology
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5293687/ https://www.ncbi.nlm.nih.gov/pubmed/28190920 http://dx.doi.org/10.1293/tox.2016-0035 |