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Acute alloxan renal toxicity in the rat initially causes degeneration of thick ascending limbs of Henle

Alloxan (AL) is a material well-known to induce diabetes. Prior to inducing a prolonged diabetic state, AL causes acute tubulointerstitial nephritis. However, the precise primary target site and mechanism of its nephrotoxicity remain unclear. The objective of this study was to evaluate the morpholog...

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Detalles Bibliográficos
Autores principales:	Terayama, Yui, Kodama, Yasushi, Matsuura, Tetsuro, Ozaki, Kiyokazu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Japanese Society of Toxicologic Pathology 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5293687/ https://www.ncbi.nlm.nih.gov/pubmed/28190920 http://dx.doi.org/10.1293/tox.2016-0035

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