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The Emerging Roles of Early Protein Folding Events in the Secretory Pathway in the Development of Neurodegenerative Maladies

Although, protein aggregation and deposition are unifying features of various neurodegenerative disorders, recent studies indicate that different mechanisms can lead to the development of the same malady. Among these, failure in early protein folding and maturation emerge as key mechanistic events t...

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Detalles Bibliográficos
Autores principales: Dubnikov, Tatyana, Cohen, Ehud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5293786/
https://www.ncbi.nlm.nih.gov/pubmed/28223916
http://dx.doi.org/10.3389/fnins.2017.00048