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Two-Pore Channels: Catalyzers of Endolysosomal Transport and Function

Two-pore channels (TPCs) have recently emerged as a novel class of non-selective cation channels in the endolysosomal system. There are two members in the human genome, TPC1 and TPC2. Studies with TPC knockout and knockdown models have revealed that these channels participate in the regulation of mu...

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Detalles Bibliográficos
Autores principales: Grimm, Christian, Chen, Cheng-Chang, Wahl-Schott, Christian, Biel, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5293812/
https://www.ncbi.nlm.nih.gov/pubmed/28223936
http://dx.doi.org/10.3389/fphar.2017.00045