Therapeutic Potential of Secreted Amyloid Precursor Protein APPsα

Cleavage of the amyloid precursor protein (APP) by α-secretase generates an extracellularly released fragment termed secreted APP-alpha (APPsα). Not only is this process of interest due to the cleavage of APP within the amyloid-beta sequence, but APPsα itself has many physiological properties that s...

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Detalles Bibliográficos
Autores principales: Mockett, Bruce G., Richter, Max, Abraham, Wickliffe C., Müller, Ulrike C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5293819/
https://www.ncbi.nlm.nih.gov/pubmed/28223920
http://dx.doi.org/10.3389/fnmol.2017.00030

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5293819/
https://www.ncbi.nlm.nih.gov/pubmed/28223920
http://dx.doi.org/10.3389/fnmol.2017.00030

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