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Therapeutic Potential of Secreted Amyloid Precursor Protein APPsα

Cleavage of the amyloid precursor protein (APP) by α-secretase generates an extracellularly released fragment termed secreted APP-alpha (APPsα). Not only is this process of interest due to the cleavage of APP within the amyloid-beta sequence, but APPsα itself has many physiological properties that s...

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Detalles Bibliográficos
Autores principales:	Mockett, Bruce G., Richter, Max, Abraham, Wickliffe C., Müller, Ulrike C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5293819/ https://www.ncbi.nlm.nih.gov/pubmed/28223920 http://dx.doi.org/10.3389/fnmol.2017.00030

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