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A Proteomic Approach to Analyze the Aspirin-mediated Lysine Acetylome

Aspirin, or acetylsalicylic acid is widely used to control pain, inflammation and fever. Important to this function is its ability to irreversibly acetylate cyclooxygenases at active site serines. Aspirin has the potential to acetylate other amino acid side-chains, leading to the possibility that as...

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Detalles Bibliográficos
Autores principales: Tatham, Michael H., Cole, Christian, Scullion, Paul, Wilkie, Ross, Westwood, Nicholas J., Stark, Lesley A., Hay, Ronald T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294217/
https://www.ncbi.nlm.nih.gov/pubmed/27913581
http://dx.doi.org/10.1074/mcp.O116.065219