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A Proteomic Approach to Analyze the Aspirin-mediated Lysine Acetylome
Aspirin, or acetylsalicylic acid is widely used to control pain, inflammation and fever. Important to this function is its ability to irreversibly acetylate cyclooxygenases at active site serines. Aspirin has the potential to acetylate other amino acid side-chains, leading to the possibility that as...
Autores principales: | Tatham, Michael H., Cole, Christian, Scullion, Paul, Wilkie, Ross, Westwood, Nicholas J., Stark, Lesley A., Hay, Ronald T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Biochemistry and Molecular Biology
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294217/ https://www.ncbi.nlm.nih.gov/pubmed/27913581 http://dx.doi.org/10.1074/mcp.O116.065219 |
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