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API5 confers cancer stem cell-like properties through the FGF2-NANOG axis

Immune selection drives the evolution of tumor cells toward an immune-resistant and cancer stem cell (CSC)-like phenotype. We reported that apoptosis inhibitor-5 (API5) acts as an immune escape factor, which has a significant role in controlling immune resistance to antigen-specific T cells, but its...

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Detalles Bibliográficos
Autores principales: Song, K-H, Cho, H, Kim, S, Lee, H-J, Oh, S J, Woo, S R, Hong, S-O, Jang, H S, Noh, K H, Choi, C H, Chung, J-Y, Hewitt, S M, Kim, J-H, Son, M, Kim, S-H, Lee, B I, Park, H-C, Bae, Y-K, Kim, T W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294250/
https://www.ncbi.nlm.nih.gov/pubmed/28092370
http://dx.doi.org/10.1038/oncsis.2016.87