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The role of the cancer stem cell marker CD271 in DNA damage response and drug resistance of melanoma cells

Several lines of evidence have suggested that stemness and acquired resistance to targeted inhibitors or chemotherapeutics are mechanistically linked. Here we observed high cell surface and total levels of nerve growth factor receptor/CD271, a marker of melanoma-initiating cells, in sub-populations...

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Detalles Bibliográficos
Autores principales: Redmer, T, Walz, I, Klinger, B, Khouja, S, Welte, Y, Schäfer, R, Regenbrecht, C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294251/
https://www.ncbi.nlm.nih.gov/pubmed/28112719
http://dx.doi.org/10.1038/oncsis.2016.88