Treatment with Sildenafil and Donepezil Improves Angiogenesis in Experimentally Induced Critical Limb Ischemia

Objectives. In this study, we aimed to demonstrate the role of sildenafil (an antagonist of phosphodiesterase type 5 (PDE-5)) and donepezil (a specific and reversible inhibitor of acetylcholinesterase (Ach)) in increasing ischemia-induced angiogenesis. Method. Critical limb ischemia was induced by l...

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Detalles Bibliográficos
Autores principales: Constantinescu, Ioana M., Bolfa, Pompei, Constantinescu, Dan, Mironiuc, Aurel I., Gherman, Claudia D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294352/
https://www.ncbi.nlm.nih.gov/pubmed/28243607
http://dx.doi.org/10.1155/2017/9532381

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294352/
https://www.ncbi.nlm.nih.gov/pubmed/28243607
http://dx.doi.org/10.1155/2017/9532381

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