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Improving the therapeutic efficacy of mesenchymal stromal cells to restore perfusion in critical limb ischemia through pulsed focused ultrasound

Mesenchymal stem cells (MSC) are promising therapeutics for critical limb ischemia (CLI). Mechanotransduction from pulsed focused ultrasound (pFUS) upregulates local chemoattractants to enhance homing of intravenously (IV)-infused MSC and improve outcomes. This study investigated whether pFUS exposu...

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Detalles Bibliográficos
Autores principales: Tebebi, Pamela A., Kim, Saejeong J., Williams, Rashida A., Milo, Blerta, Frenkel, Victor, Burks, Scott R., Frank, Joseph A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294408/
https://www.ncbi.nlm.nih.gov/pubmed/28169278
http://dx.doi.org/10.1038/srep41550