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Loss of HSulf-1: The Missing Link between Autophagy and Lipid Droplets in Ovarian Cancer

Defective autophagy and deranged metabolic pathways are common in cancer; pharmacologic targeting of these two pathways could provide a viable therapeutic option. However, how these pathways are regulated by limited availability of growth factors is still unknown. Our study shows that HSulf-1 (endos...

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Detalles Bibliográficos
Autores principales: Roy, Debarshi, Mondal, Susmita, Khurana, Ashwani, Jung, Deok-Beom, Hoffmann, Robert, He, Xiaoping, Kalogera, Eleftheria, Dierks, Thomas, Hammond, Edward, Dredge, Keith, Shridhar, Viji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294412/
https://www.ncbi.nlm.nih.gov/pubmed/28169314
http://dx.doi.org/10.1038/srep41977