DNA methylation governs the dynamic regulation of inflammation by apoptotic cells during efferocytosis

Efficient clearance of apoptotic cells (AC) is pivotal in preventing autoimmunity and is a potent immunosuppressive stimulus. However, activation of cells prior to apoptosis abolishes their immunoregulatory properties. Here we show using the antigen-induced model of arthritis that the degree of DNA...

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Detalles Bibliográficos
Autores principales: Notley, Clare A., Jordan, Christine K., McGovern, Jenny L., Brown, Mark A., Ehrenstein, Michael R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294421/
https://www.ncbi.nlm.nih.gov/pubmed/28169339
http://dx.doi.org/10.1038/srep42204

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294421/
https://www.ncbi.nlm.nih.gov/pubmed/28169339
http://dx.doi.org/10.1038/srep42204

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