Omega-3 and omega-6 DPA equally inhibit the sphingosylphosphorylcholine-induced Ca(2+)-sensitization of vascular smooth muscle contraction via inhibiting Rho-kinase activation and translocation

We previously reported that eicosapentaenoic acid (EPA), an omega-3 polyunsaturated fatty acid (n-3 PUFA), effectively inhibits sphingosylphosphorylcholine (SPC)-induced Ca(2+)-sensitization of vascular smooth muscle (VSM) contraction which is a major cause of cardiovascular and cerebrovascular vaso...

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Detalles Bibliográficos
Autores principales: Zhang, Ying, Zhang, Min, Lyu, Bochao, Kishi, Hiroko, Kobayashi, Sei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294466/
https://www.ncbi.nlm.nih.gov/pubmed/28169288
http://dx.doi.org/10.1038/srep36368

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294466/
https://www.ncbi.nlm.nih.gov/pubmed/28169288
http://dx.doi.org/10.1038/srep36368

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