Antitumour activity of trabectedin in myelodysplastic/myeloproliferative neoplasms

BACKGROUND: Juvenile myelomonocytic leukaemia (JMML) and chronic myelomonocytic leukaemia (CMML) are myelodysplastic myeloproliferative (MDS/MPN) neoplasms with unfavourable prognosis and without effective chemotherapy treatment. Trabectedin is a DNA minor groove binder acting as a modulator of tran...

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Detalles Bibliográficos
Autores principales: Romano, Michela, Della Porta, Matteo Giovanni, Gallì, Anna, Panini, Nicolò, Licandro, Simonetta Andrea, Bello, Ezia, Craparotta, Ilaria, Rosti, Vittorio, Bonetti, Elisa, Tancredi, Richard, Rossi, Marianna, Mannarino, Laura, Marchini, Sergio, Porcu, Luca, Galmarini, Carlos M, Zambelli, Alberto, Zecca, Marco, Locatelli, Franco, Cazzola, Mario, Biondi, Andrea, Rambaldi, Alessandro, Allavena, Paola, Erba, Eugenio, D'Incalci, Maurizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294481/
https://www.ncbi.nlm.nih.gov/pubmed/28072764
http://dx.doi.org/10.1038/bjc.2016.424

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294481/
https://www.ncbi.nlm.nih.gov/pubmed/28072764
http://dx.doi.org/10.1038/bjc.2016.424

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