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The impact of body composition parameters on ipilimumab toxicity and survival in patients with metastatic melanoma

BACKGROUND: Body composition is an important predictor of drug toxicity and outcome. Ipilimumab (Ipi), a monoclonal antibody used to treat metastatic melanoma, has specific toxicities. No validated biomarkers that predict Ipi toxicity and efficacy exist. Also, the impact of Ipi on body composition h...

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Detalles Bibliográficos
Autores principales: Daly, Louise E, Power, Derek G, O'Reilly, Áine, Donnellan, Paul, Cushen, Samantha J, O'Sullivan, Kathleen, Twomey, Maria, Woodlock, David P, Redmond, Henry P, Ryan, Aoife M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294486/
https://www.ncbi.nlm.nih.gov/pubmed/28072766
http://dx.doi.org/10.1038/bjc.2016.431