CYP3A7*1C allele is associated with reduced levels of 2-hydroxylation pathway oestrogen metabolites

BACKGROUND: Endogenous sex hormones are well-established risk factors for breast cancer; the contribution of specific oestrogen metabolites (EMs) and/or ratios of specific EMs is less clear. We have previously identified a CYP3A7*1C allele that is associated with lower urinary oestrone (E(1)) levels...

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Detalles Bibliográficos
Autores principales: Sood, Deepti, Johnson, Nichola, Jain, Pooja, Siskos, Alexandros P, Bennett, Mark, Gilham, Clare, Busana, Marta Cecilia, Peto, Julian, dos-Santos-Silva, Isabel, Keun, Hector C, Fletcher, Olivia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Genetics & Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294487/
https://www.ncbi.nlm.nih.gov/pubmed/28072767
http://dx.doi.org/10.1038/bjc.2016.432

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294487/
https://www.ncbi.nlm.nih.gov/pubmed/28072767
http://dx.doi.org/10.1038/bjc.2016.432

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