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CYP3A7*1C allele is associated with reduced levels of 2-hydroxylation pathway oestrogen metabolites

BACKGROUND: Endogenous sex hormones are well-established risk factors for breast cancer; the contribution of specific oestrogen metabolites (EMs) and/or ratios of specific EMs is less clear. We have previously identified a CYP3A7*1C allele that is associated with lower urinary oestrone (E(1)) levels...

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Detalles Bibliográficos
Autores principales:	Sood, Deepti, Johnson, Nichola, Jain, Pooja, Siskos, Alexandros P, Bennett, Mark, Gilham, Clare, Busana, Marta Cecilia, Peto, Julian, dos-Santos-Silva, Isabel, Keun, Hector C, Fletcher, Olivia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Genetics & Genomics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294487/ https://www.ncbi.nlm.nih.gov/pubmed/28072767 http://dx.doi.org/10.1038/bjc.2016.432

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