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Diagnosis of pancreaticobiliary malignancy by detection of minichromosome maintenance protein 5 in biliary brush cytology

BACKGROUND: Biliary brush cytology is the standard method of evaluating biliary strictures, but is insensitive at detecting malignancy. In pancreaticobiliary cancer minichromosome maintenance replication proteins (MCM 2–7) are dysregulated in the biliary epithelium and MCM5 levels are elevated in bi...

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Detalles Bibliográficos
Autores principales: Keane, Margaret G, Huggett, Matthew T, Chapman, Michael H, Johnson, Gavin J, Webster, George J, Thorburn, Douglas, Mackay, James, Pereira, Stephen P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294492/
https://www.ncbi.nlm.nih.gov/pubmed/28081547
http://dx.doi.org/10.1038/bjc.2016.447