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Diagnosis of pancreaticobiliary malignancy by detection of minichromosome maintenance protein 5 in biliary brush cytology
BACKGROUND: Biliary brush cytology is the standard method of evaluating biliary strictures, but is insensitive at detecting malignancy. In pancreaticobiliary cancer minichromosome maintenance replication proteins (MCM 2–7) are dysregulated in the biliary epithelium and MCM5 levels are elevated in bi...
Autores principales: | Keane, Margaret G, Huggett, Matthew T, Chapman, Michael H, Johnson, Gavin J, Webster, George J, Thorburn, Douglas, Mackay, James, Pereira, Stephen P |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294492/ https://www.ncbi.nlm.nih.gov/pubmed/28081547 http://dx.doi.org/10.1038/bjc.2016.447 |
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