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Human CD64-targeted non-viral siRNA delivery system for blood monocyte gene modulation

A subset of phagocytes including inflammatory monocytes in blood migrate and give rise to macrophages in inflammatory tissues which generated the idea that blood monocytes are the therapeutic targets for drug delivery. Fc gamma receptor I (CD64) is a membrane receptor for the Fc region of immunoglob...

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Detalles Bibliográficos
Autores principales: Yong, Seok-Beom, Kim, Hyung Jin, Kim, Jang Kyoung, Chung, Jee Young, Kim, Yong-Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294565/
https://www.ncbi.nlm.nih.gov/pubmed/28169353
http://dx.doi.org/10.1038/srep42171