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Stoichiometry and structure of a lantibiotic maturation complex

Lantibiotics are ribosomally synthesized antimicrobial peptides secreted by mainly Gram-positive bacteria. Class 1 lantibiotics mature via two modification steps introduced by a modification LanBC complex. For the lantibiotic nisin, the dehydratase NisB catalyzes the dehydration of serine and threon...

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Detalles Bibliográficos
Autores principales: Reiners, Jens, Abts, André, Clemens, Rebecca, Smits, Sander H. J., Schmitt, Lutz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294574/
https://www.ncbi.nlm.nih.gov/pubmed/28169337
http://dx.doi.org/10.1038/srep42163