Anti-apoptotic effects of Sonic hedgehog signalling through oxidative stress reduction in astrocytes co-cultured with excretory-secretory products of larval Angiostrongylus cantonensis

Angiostrongylus cantonensis, the rat lungworm, is an important aetiologic agent of eosinophilic meningitis and meningoencephalitis in humans. Co-culturing astrocytes with soluble antigens of A. cantonensis activated the Sonic hedgehog (Shh) signalling pathway and inhibited the apoptosis of astrocyte...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Kuang-Yao, Chiu, Cheng-Hsun, Wang, Lian-Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294578/
https://www.ncbi.nlm.nih.gov/pubmed/28169282
http://dx.doi.org/10.1038/srep41574

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294578/
https://www.ncbi.nlm.nih.gov/pubmed/28169282
http://dx.doi.org/10.1038/srep41574

Ejemplares similares