Chloroquine inhibits human CD4(+) T-cell activation by AP-1 signaling modulation

Chloroquine (CQ) is widely used as an anti-inflammatory therapeutic for rheumatic diseases. Although its modes of action on the innate immune system are well described, there is still insufficient knowledge about its direct effects on the adaptive immune system. Thus, we evaluated the influence of C...

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Detalles Bibliográficos
Autores principales: Schmidt, Ralf L. J., Jutz, Sabrina, Goldhahn, Katrin, Witzeneder, Nadine, Gerner, Marlene C., Trapin, Doris, Greiner, Georg, Hoermann, Gregor, Steiner, Guenter, Pickl, Winfried F., Burgmann, Heinz, Steinberger, Peter, Ratzinger, Franz, Schmetterer, Klaus G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294581/
https://www.ncbi.nlm.nih.gov/pubmed/28169350
http://dx.doi.org/10.1038/srep42191

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294581/
https://www.ncbi.nlm.nih.gov/pubmed/28169350
http://dx.doi.org/10.1038/srep42191

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