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Hedgehog Pathway Inhibition Hampers Sphere and Holoclone Formation in Rhabdomyosarcoma

Rhabdomyosarcoma (RMS) is the most common type of soft tissue sarcoma in children and can be divided into two main subtypes: embryonal (eRMS) and alveolar (aRMS). Among the cellular heterogeneity of tumors, the existence of a small fraction of cells called cancer stem cells (CSC), thought to be resp...

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Detalles Bibliográficos
Autores principales: Almazán-Moga, Ana, Zarzosa, Patricia, Vidal, Isaac, Molist, Carla, Giralt, Irina, Navarro, Natalia, Soriano, Aroa, Segura, Miguel F., Alfranca, Arantza, Garcia-Castro, Javier, Sánchez de Toledo, José, Roma, Josep, Gallego, Soledad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294584/
https://www.ncbi.nlm.nih.gov/pubmed/28243259
http://dx.doi.org/10.1155/2017/7507380