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Sequestration of Ribosome during Protein Aggregate Formation: Contribution of ribosomal RNA

An understanding of the mechanisms underlying protein aggregation and cytotoxicity of the protein aggregates is crucial in the prevention of several diseases in humans. Ribosome, the cellular protein synthesis machine is capable of acting as a protein folding modulator. The peptidyltransferase cente...

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Detalles Bibliográficos
Autores principales: Pathak, Bani K., Mondal, Surojit, Banerjee, Senjuti, Ghosh, Amar Nath, Barat, Chandana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294636/
https://www.ncbi.nlm.nih.gov/pubmed/28169307
http://dx.doi.org/10.1038/srep42017