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Sequestration of Ribosome during Protein Aggregate Formation: Contribution of ribosomal RNA
An understanding of the mechanisms underlying protein aggregation and cytotoxicity of the protein aggregates is crucial in the prevention of several diseases in humans. Ribosome, the cellular protein synthesis machine is capable of acting as a protein folding modulator. The peptidyltransferase cente...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294636/ https://www.ncbi.nlm.nih.gov/pubmed/28169307 http://dx.doi.org/10.1038/srep42017 |