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Utilizing Selected Di- and Trinucleotides of siRNA to Predict RNAi Activity

Small interfering RNAs (siRNAs) induce posttranscriptional gene silencing in various organisms. siRNAs targeted to different positions of the same gene show different effectiveness; hence, predicting siRNA activity is a crucial step. In this paper, we developed and evaluated a powerful tool named “s...

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Detalles Bibliográficos
Autores principales: Han, Ye, Liu, Yuanning, Zhang, Hao, He, Fei, Shu, Chonghe, Dong, Liyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294759/
https://www.ncbi.nlm.nih.gov/pubmed/28243313
http://dx.doi.org/10.1155/2017/5043984