Cytotoxic T cells modulate inflammation and endogenous opioid analgesia in chronic arthritis

BACKGROUND: This study examined the development of chronic pain, a cardinal symptom of rheumatoid arthritis (RA), in mice with antigen- and collagen-induced arthritis (ACIA). Since the role of CD8(+) T cells in arthritis is controversial, we investigated the consequences of CD8-depletion on arthriti...

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Detalles Bibliográficos
Autores principales: Baddack-Werncke, Uta, Busch-Dienstfertig, Melanie, González-Rodríguez, Sara, Maddila, Santhosh Chandar, Grobe, Jenny, Lipp, Martin, Stein, Christoph, Müller, Gerd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294766/
https://www.ncbi.nlm.nih.gov/pubmed/28166793
http://dx.doi.org/10.1186/s12974-017-0804-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294766/
https://www.ncbi.nlm.nih.gov/pubmed/28166793
http://dx.doi.org/10.1186/s12974-017-0804-y

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