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Toll-like receptor 3 activation selectively reverses HIV latency in microglial cells

BACKGROUND: Multiple toll-like receptors (TLRs) are expressed in cells of the monocytic lineage, including microglia, which constitute the major reservoir for human immunodeficiency virus (HIV) infection in the brain. We hypothesized that TLR receptor mediated responses to inflammatory conditions by...

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Detalles Bibliográficos
Autores principales: Alvarez-Carbonell, David, Garcia-Mesa, Yoelvis, Milne, Stephanie, Das, Biswajit, Dobrowolski, Curtis, Rojas, Roxana, Karn, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294768/
https://www.ncbi.nlm.nih.gov/pubmed/28166799
http://dx.doi.org/10.1186/s12977-017-0335-8