Cargando…

Merlin controls the repair capacity of Schwann cells after injury by regulating Hippo/YAP activity

Loss of the Merlin tumor suppressor and activation of the Hippo signaling pathway play major roles in the control of cell proliferation and tumorigenesis. We have identified completely novel roles for Merlin and the Hippo pathway effector Yes-associated protein (YAP) in the control of Schwann cell (...

Descripción completa

Detalles Bibliográficos
Autores principales: Mindos, Thomas, Dun, Xin-peng, North, Katherine, Doddrell, Robin D.S., Schulz, Alexander, Edwards, Philip, Russell, James, Gray, Bethany, Roberts, Sheridan L., Shivane, Aditya, Mortimer, Georgina, Pirie, Melissa, Zhang, Nailing, Pan, Duojia, Morrison, Helen, Parkinson, David B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294779/
https://www.ncbi.nlm.nih.gov/pubmed/28137778
http://dx.doi.org/10.1083/jcb.201606052