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Merlin controls the repair capacity of Schwann cells after injury by regulating Hippo/YAP activity
Loss of the Merlin tumor suppressor and activation of the Hippo signaling pathway play major roles in the control of cell proliferation and tumorigenesis. We have identified completely novel roles for Merlin and the Hippo pathway effector Yes-associated protein (YAP) in the control of Schwann cell (...
Autores principales: | Mindos, Thomas, Dun, Xin-peng, North, Katherine, Doddrell, Robin D.S., Schulz, Alexander, Edwards, Philip, Russell, James, Gray, Bethany, Roberts, Sheridan L., Shivane, Aditya, Mortimer, Georgina, Pirie, Melissa, Zhang, Nailing, Pan, Duojia, Morrison, Helen, Parkinson, David B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294779/ https://www.ncbi.nlm.nih.gov/pubmed/28137778 http://dx.doi.org/10.1083/jcb.201606052 |
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