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Human basonuclin 2 up-regulates a cascade set of interferon-stimulated genes with anti-cancerous properties in a lung cancer model

BACKGROUND: Human basonuclin 2 (BNC2) acts as a tumor suppressor in multiple cancers in an as yet unidentified manner. The role and expression of the BNC2 gene in lung cancer has not yet been investigated. METHODS: BNC2 expression was studied in the A549 and BEAS-2B cell lines, as well as in lung ca...

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Detalles Bibliográficos
Autores principales: Urgard, Egon, Reigo, Anu, Reinmaa, Eva, Rebane, Ana, Metspalu, Andres
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294813/
https://www.ncbi.nlm.nih.gov/pubmed/28184177
http://dx.doi.org/10.1186/s12935-017-0394-x