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Mechanism of action of trabectedin in desmoplastic small round cell tumor cells

BACKGROUND: Desmoplastic small round cell tumor (DSRCT) is a rare and highly aggressive disease, that can be described as a member of the family of small round blue cell tumors. The molecular diagnostic marker is the t(11;22)(p13;q12) translocation, which creates an aberrant transcription factor, EW...

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Detalles Bibliográficos
Autores principales: Uboldi, S., Craparotta, I., Colella, G., Ronchetti, E., Beltrame, L., Vicario, S., Marchini, S., Panini, N., Dagrada, G., Bozzi, F., Pilotti, S., Galmarini, C. M., D’Incalci, M., Gatta, R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294815/
https://www.ncbi.nlm.nih.gov/pubmed/28166781
http://dx.doi.org/10.1186/s12885-017-3091-1