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Not all predicted CRISPR–Cas systems are equal: isolated cas genes and classes of CRISPR like elements

BACKGROUND: The CRISPR–Cas systems in prokaryotes are RNA-guided immune systems that target and deactivate foreign nucleic acids. A typical CRISPR–Cas system consists of a CRISPR array of repeat and spacer units, and a locus of cas genes. The CRISPR and the cas locus are often located next to each o...

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Detalles Bibliográficos
Autores principales: Zhang, Quan, Ye, Yuzhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294841/
https://www.ncbi.nlm.nih.gov/pubmed/28166719
http://dx.doi.org/10.1186/s12859-017-1512-4