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5-hydroxytryptamine synthesized in the aorta-gonad-mesonephros regulates hematopoietic stem and progenitor cell survival

The in vitro or ex vivo production of transplantable hematopoietic stem cells (HSCs) holds great promise for the treatment of hematological diseases in the clinic. However, HSCs have not been produced from either embryonic or induced pluripotent stem cells. In this study, we report that 5-hydroxytry...

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Detalles Bibliográficos
Autores principales: Lv, Junhua, Wang, Lu, Gao, Ya, Ding, Yu-Qiang, Liu, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294845/
https://www.ncbi.nlm.nih.gov/pubmed/28031476
http://dx.doi.org/10.1084/jem.20150906