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CNS-targeted autoimmunity leads to increased influenza mortality in mice

The discovery that central nervous system (CNS)–targeted autoreactive T cells required a process of licensing in the lung revealed an unexpected relationship between these organs. The clinical and immunological significance of this finding is bidirectional in that it showed not only a mechanism by w...

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Detalles Bibliográficos
Autores principales: Glenn, Justin D., Smith, Matthew D., Xue, Pei, Chan-Li, Yee, Collins, Samuel, Calabresi, Peter A., Horton, Maureen R., Whartenby, Katharine A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294848/
https://www.ncbi.nlm.nih.gov/pubmed/28057805
http://dx.doi.org/10.1084/jem.20160517