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CNS-targeted autoimmunity leads to increased influenza mortality in mice
The discovery that central nervous system (CNS)–targeted autoreactive T cells required a process of licensing in the lung revealed an unexpected relationship between these organs. The clinical and immunological significance of this finding is bidirectional in that it showed not only a mechanism by w...
Autores principales: | Glenn, Justin D., Smith, Matthew D., Xue, Pei, Chan-Li, Yee, Collins, Samuel, Calabresi, Peter A., Horton, Maureen R., Whartenby, Katharine A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294848/ https://www.ncbi.nlm.nih.gov/pubmed/28057805 http://dx.doi.org/10.1084/jem.20160517 |
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