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Strong adhesion by regulatory T cells induces dendritic cell cytoskeletal polarization and contact-dependent lethargy

Dendritic cells are targeted by regulatory T (T reg) cells, in a manner that operates as an indirect mode of T cell suppression. In this study, using a combination of single-cell force spectroscopy and structured illumination microscopy, we analyze individual T reg cell–DC interaction events and sho...

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Detalles Bibliográficos
Autores principales: Chen, Jiahuan, Ganguly, Anutosh, Mucsi, Ashley D., Meng, Junchen, Yan, Jiacong, Detampel, Pascal, Munro, Fay, Zhang, Zongde, Wu, Mei, Hari, Aswin, Stenner, Melanie D., Zheng, Wencheng, Kubes, Paul, Xia, Tie, Amrein, Matthias W., Qi, Hai, Shi, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294852/
https://www.ncbi.nlm.nih.gov/pubmed/28082358
http://dx.doi.org/10.1084/jem.20160620