Efficient confidence limits for adaptive one-arm two-stage clinical trials with binary endpoints

BACKGROUND: Recently, several adaptive one-arm two-stage designs have been developed by fully using the information from previous stages to reduce the expected sample size in clinical trials with binary endpoints as primary outcome. It is important to compute exact confidence limits for these studie...

Descripción completa

Detalles Bibliográficos
Autores principales: Shan, Guogen, Zhang, Hua, Jiang, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294881/
https://www.ncbi.nlm.nih.gov/pubmed/28166741
http://dx.doi.org/10.1186/s12874-017-0297-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294881/
https://www.ncbi.nlm.nih.gov/pubmed/28166741
http://dx.doi.org/10.1186/s12874-017-0297-5

Ejemplares similares