Tumour-associated glial host cells display a stem-like phenotype with a distinct gene expression profile and promote growth of GBM xenografts

BACKGROUND: Little is known about the role of glial host cells in brain tumours. However, supporting stromal cells have been shown to foster tumour growth in other cancers. METHODS: We isolated stromal cells from patient-derived glioblastoma (GBM) xenografts established in GFP-NOD/scid mice. With si...

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Detalles Bibliográficos
Autores principales: Leiss, Lina, Mutlu, Ercan, Øyan, Anne, Yan, Tao, Tsinkalovsky, Oleg, Sleire, Linda, Petersen, Kjell, Rahman, Mohummad Aminur, Johannessen, Mireille, Mitra, Sidhartha S., Jacobsen, Hege K., Talasila, Krishna M., Miletic, Hrvoje, Jonassen, Inge, Li, Xingang, Brons, Nicolaas H., Kalland, Karl-Henning, Wang, Jian, Enger, Per Øyvind
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294893/
https://www.ncbi.nlm.nih.gov/pubmed/28173797
http://dx.doi.org/10.1186/s12885-017-3109-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294893/
https://www.ncbi.nlm.nih.gov/pubmed/28173797
http://dx.doi.org/10.1186/s12885-017-3109-8

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