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Identification of influenza A nucleoprotein body domain residues essential for viral RNA expression expose antiviral target

BACKGROUND: Influenza A virus is controlled with yearly vaccination while emerging global pandemics are kept at bay with antiviral medications. Unfortunately, influenza A viruses have emerged resistance to approved influenza antivirals. Accordingly, there is an urgent need for novel antivirals to co...

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Detalles Bibliográficos
Autores principales: Davis, Alicia M., Ramirez, Jose, Newcomb, Laura L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294902/
https://www.ncbi.nlm.nih.gov/pubmed/28173821
http://dx.doi.org/10.1186/s12985-017-0694-8