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The Effects of Ascorbate, N-Acetylcysteine, and Resveratrol on Fibroblasts from Patients with Mitochondrial Disorders

Reactive oxygen species (ROS) are assumed to be implicated in the pathogenesis of inborn mitochondrial diseases affecting oxidative phosphorylation (OXPHOS). In the current study, we characterized the effects of three small molecules with antioxidant properties (N-acetylcysteine, ascorbate, and resv...

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Detalles Bibliográficos
Autores principales: Douiev, Liza, Soiferman, Devorah, Alban, Corinne, Saada, Ann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294954/
https://www.ncbi.nlm.nih.gov/pubmed/28025489
http://dx.doi.org/10.3390/jcm6010001