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Error-Free Bypass of 7,8-dihydro-8-oxo-2′-deoxyguanosineby DNA Polymerase of Pseudomonas aeruginosa Phage PaP1

As one of the most common forms of oxidative DNA damage, 7,8-dihydro-8-oxo-2′-deoxyguanosine (8-oxoG) generally leads to G:C to T:A mutagenesis. To study DNA replication encountering 8-oxoG by the sole DNA polymerase (Gp90) of Pseudomonas aeruginosa phage PaP1, we performed steady-state and pre-stea...

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Detalles Bibliográficos
Autores principales: Gu, Shiling, Xue, Qizhen, Liu, Qin, Xiong, Mei, Wang, Wanneng, Zhang, Huidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295013/
https://www.ncbi.nlm.nih.gov/pubmed/28067844
http://dx.doi.org/10.3390/genes8010018